A clinical risk model scores your pattern — mechanical wear or inflammatory signals — and explains what it means in plain language. The routing is physician-designed and mapped to published clinical criteria (ACR/EULAR, AAOS): orthopedic surgeon, rheumatologist, or the preventive habits that protect the joints you have. Not a diagnosis. A direction.
Back pain rather than a joint? Take the back-pain check →
10 questions. About 2 minutes. Everything runs locally — no data is collected or stored.
Why this isn't a symptom-checker
Any AI will now guess at what your joint pain means. The hard part was never the guess — it's a direction you're safe to act on. Your result routed on criteria a physician designed and mapped to published guidelines (ACR/EULAR, AAOS), not a generated opinion. When you take it to a real clinician, it's built to line up with how they already think — not something they have to unwind.
After your score
It's easy to leave a joint-pain visit having answered questions instead of asking them. Flip that. Your results give you a pattern — and the pattern tells you what's worth asking. A clinician can do more with a specific question and a clear history than with “it just hurts.” Walk in with one page and one good question, and the fifteen minutes start working for you. This is preparation, not medical advice — your clinician's exam and judgment lead, and if she sees things differently than your results do, that conversation is exactly what you came for.
A one-page brief of your results: your pattern, the joints involved, how long it’s been going on, what makes it better or worse, and what you’ve already tried. Five lines a clinician can read in thirty seconds.
One question matched to your route. If your pattern leans inflammatory: “Do my symptoms warrant labs or a rheumatology referral?” If it leans mechanical: “Would an X-ray change the plan — and what would we do differently depending on what it shows?”
A good answer engages with your pattern. If your clinician sees it differently, that’s useful — ask what she’s noticing that points another direction. She may recommend something your results didn’t. Coming in prepared is what makes that conversation possible.
Ten validated risk signals drawn from published clinical evidence. Each one maps directly to a question in the assessment above.
Your answers plot you on two independent axes — structural load and inflammatory signal. Where you land decides which of four routes fits.
Mechanical pathway
Orthopedic surgery
High BMI, prior joint injury, age, activity pattern. Structural wear that eases with rest. Route: orthopedic evaluation and outcome tracking.
Inflammatory pathway
Rheumatology
Morning stiffness over 30 minutes, multi-joint involvement, recurrent swelling. Immune-mediated. Route: rheumatology evaluation.
Mixed pathway
Multidisciplinary
Both axes elevated — common and easy to mismanage. Route: a coordinated work-up so neither component is left to progress.
Low signal
Prevention + education
Neither pattern strongly expressed. Route: weight, movement, anti-inflammatory nutrition, and monitoring if symptoms shift.
The mechanical and prevention routes both end in the same question — is your mobility actually changing? Walking speed is the objective way to know. Get your gait number — free, 60 seconds →
Mechanical and inflammatory arthritis are treated by different specialists using different drugs. The distinction between them is the most important diagnostic question in joint pain. Morning stiffness duration is the single fastest clinical signal.
| Feature | Mechanical (OA) | Inflammatory (RA) |
|---|---|---|
| When is pain worst? | After activity, end of day | At rest and in the morning |
| Does movement help? | Initially, but worsens with overuse | Yes — stiffness loosens with movement |
| Morning stiffness duration | Under 30 minutes — usually under 15 | Over 60 minutes, often 1–4 hours |
| Which joints? | Weight-bearing: knees, hips, spine | Symmetric small joints: hands, wrists, feet |
| Joint distribution | Asymmetric, single or few joints | Symmetric, multiple joints simultaneously |
| Systemic symptoms | Rare — localized problem | Fatigue, low-grade fever, weight loss |
| Blood tests | Normal RF, ESR, CRP | Elevated RF, anti-CCP (70–80% of RA), CRP |
| X-ray findings | Osteophytes, joint space narrowing | Joint erosions, periarticular osteoporosis |
| Who develops it? | Over 45, higher BMI, prior injury | Women 2–3× more; any age; autoimmune triggers |
Sources: ACR 2021 RA Classification Criteria (Aletaha et al.); ACR OA Guideline 2022; EULAR OA Recommendations 2019; StatPearls NBK430728.
This comparison is for education only and does not constitute a diagnosis. Many patients present with overlapping or atypical features. A physician evaluation — including blood tests and imaging — is required to distinguish these conditions definitively.
If your assessment pointed toward an inflammatory pattern, one lab test matters above all others: anti-cyclic citrullinated peptide (anti-CCP) antibody. It predicts RA with 95% specificity — meaning a positive result is highly unlikely to be a false alarm. It can be detectable years before symptoms begin.
67%
Sensitivity
2 in 3 RA patients test positive
95%
Specificity
Only 1 in 20 positives is a false alarm
3–5 yrs
Detectable before symptoms
Nishimura et al., Ann Intern Med 2007
Seropositive vs seronegative RA: what the test result changes
| Clinical feature | Anti-CCP positive (seropositive) | Anti-CCP negative (seronegative) |
|---|---|---|
| Likelihood of true RA | Very high — specific marker | Still possible; other criteria apply |
| Erosive joint damage | More aggressive — erosions more common | Milder course in most patients |
| Response to biologic therapy | Strong response to anti-TNF agents | Variable; may respond to rituximab |
| Prognosis | Earlier, more aggressive treatment usually needed | More favorable long-term functional outcome |
| Speed to rheumatologist | Urgent referral — within 6 weeks of onset | Still refer; rule out other inflammatory conditions |
Questions to bring to your rheumatologist
The window of opportunity is real
Joint erosions in RA can develop within the first months of active disease and are largely irreversible. The 2021 ACR RA guideline recommends starting DMARD therapy as soon as RA is confirmed — methotrexate first, biologic agents added if insufficient response. Waiting longer than 6–12 weeks from symptom onset measurably worsens long-term outcomes. (ACR RA Guideline 2021; van der Helm-van Mil AH et al., Arthritis Rheum 2005)
Sources: Nishimura K et al., Ann Intern Med 2007; Aletaha D et al., Arthritis Rheum 2010; Nielen MM et al., Arthritis Rheum 2004; ACR RA Guideline 2021.
Get care coordination while you wait for a rheumatologistOsteoarthritis — Mechanical Wear
OA affects over 528 million people worldwide and is the most common joint disease. It is NOT simply "wear and tear" — it is progressive cartilage failure driven by mechanical overload, metabolic factors, and aging. Most people over 60 have radiographic OA in at least one joint, yet only half have symptoms. Knees bear 4× body weight with each step; hips bear 3–5× body weight on stairs. (GBD 2019; ACR OA Guideline 2022)
Rheumatoid Arthritis — Autoimmune Attack
RA affects approximately 1% of adults globally — roughly 1.5 million Americans. It is an autoimmune disease in which the immune system attacks the synovial joint lining. Untreated, RA can cause joint erosions that may develop within the first months of onset, and established joint damage is often permanent. This is why the "window of opportunity" matters — starting treatment within roughly the first 12 weeks substantially reduces long-term joint damage. Anti-CCP antibody is 70–80% sensitive and 95% specific for RA. (ACR RA Guideline 2021; Aletaha et al. 2010)
Morning Stiffness — The Fastest Clinical Signal
Morning stiffness duration distinguishes mechanical from inflammatory arthritis more reliably than any single imaging finding. Under 30 minutes (usually under 15) points to osteoarthritis — cartilage "gelling" after rest. Over 60 minutes, often 1–4 hours, that improves with movement points to inflammatory arthritis such as RA. Tracking your morning stiffness duration is the most useful thing you can do before seeing a specialist. (ACR RA Classification Criteria 2010; EULAR OA Recommendations 2019)
Risk Factors — What the Evidence Shows
OA: age over 45, BMI over 30, prior joint injury, female sex for knee OA, repetitive occupational loading (construction, nursing). Genetic factors account for 40–65% of OA risk. RA: female sex (2–3× higher risk), family history, smoking (the strongest modifiable environmental risk factor for RA), and age 30–60 at peak onset. Every pound of body weight adds approximately 4 pounds of force to the knee — losing 10 lbs reduces knee OA progression significantly. (ACR; Arthritis Foundation; Felson DT et al.)
Physical Therapy — What Actually Works
For OA: strengthening the quadriceps reduces knee pain by approximately 2–3% for every 1% increase in muscle strength. Aquatic exercise and cycling preserve joint health with minimal load. Walking is beneficial — not harmful — for knee OA and is associated with a 40% reduction in new frequent knee pain over 4 years. For RA: land-based exercise is safe during stable disease and improves physical function without increasing disease activity. A physical therapist should guide the specific program. (Lo GH et al., Arthritis Care Res 2019; Cochrane OA Exercise Reviews 2017–2023; ACR OA Guideline 2022)
When Surgery Helps — and When It Doesn't
Total knee replacement (TKA) and total hip replacement (THA) are among the highest-value procedures in medicine for end-stage OA — 90%+ of patients report significant pain relief, and implant survival exceeds 15–20 years in most registries. Surgery helps when conservative care (exercise, weight management, PT, injections) has been genuinely exhausted. Surgery does NOT reverse RA — that requires DMARDs and biologic agents. A rheumatologist should lead RA management; an orthopedic surgeon addresses structural joint failure when reconstruction is appropriate. (NJR 2023; ACR; AAOS OA Guideline 2022)
See a healthcare provider if you experience any of these.
Research has documented a consistent pattern in medicine: women’s pain is more likely to be attributed to psychological causes, and women wait significantly longer for pain treatment than men presenting with the same symptoms. This matters for joint disease specifically. Women have 2–3× the risk of rheumatoid arthritis and develop knee osteoarthritis at higher rates after age 50—yet are less likely to be referred for specialist evaluation with identical symptoms.
Hoffmann DE, Tarzian AJ. The Girl Who Cried Pain: A Bias Against Women in the Treatment of Pain. J Law Med Ethics 2001;29(1):13–27.
Three things that change the dynamic:
Research on surgical patient education shows that patients who complete structured pre-operative preparation follow through on prescribed physical therapy at nearly 5× the rate of those who do not. If you reach surgery, being prepared changes your outcome. Learn about pre-op preparation for arthroscopy.
GLP-1 medications reduce joint pain and significantly lower the long-term risk of knee replacement—weight loss is the most powerful non-surgical intervention for osteoarthritis. A 2025 analysis found tirzepatide and semaglutide more cost-effective for knee OA management than conventional weight loss programs. But there is a clinical balance: rapid weight loss without structured resistance training causes muscle loss that can complicate surgical recovery if surgery is eventually needed.
BMJ Group, 2024; Brigham Health on a Mission, Dec 2025; Monitoring Sarcopenia with Incretin Receptor Activator Treatment, PMC 2025.
Three things to track while you are on GLP-1 treatment:
If joint pain persists despite GLP-1 treatment, structured pre-surgical preparation changes recovery outcomes—including muscle preservation protocols specific to patients losing weight before orthopedic procedures. Learn about prehab for patients on GLP-1 medications.
Pain type is the fastest diagnostic signal. Two patterns, two specialists. Select the one that fits — you'll see a personalized tracking plan for that pathway.
The joint-care journey — you just took the first step